Major League 2 and Major League: Back to the Minors followed, though Sheen seems to feel that the threequel should be disregarded and any new film be treated as a true “Major League 3”. His exact words were apparently that Back to the Minors was “an abortion” and shouldn’t be considered as an official franchise entry. Not mincing his words there then.
All we have at the moment is that Sheen would like to make a new Major League film if it were greenlit, though there is no indication at the moment of any desire to make a new franchise entry. Whether Sheen will get to play “Wild Thing” again, only time will tell.
Source: TMZ, via Hollywood Reporter.