Kieran Culkin and Emma Stone in Movie 43Movie 43 has by far one of the best ensemble casts of any comedy in recent memory, and more than that, it has a terrific roster of directors at the helm for what promises to be a brilliant comedy in the New Year.

We most recently saw the film’s green-band trailer last month, and now Yahoo Movies have debuted a new red-band preview, which is, as you can imagine, highly unsuitable for work.

“Once you see it, you can’t unsee it.

From the twisted minds of producers Peter Farrelly (Hall Pass, Shallow Hal) and Charles Wessler (There’s Something About Mary, Dumb & Dumber), comes Movie 43– the outrageous new ensemble comedy starring some of the biggest names in Hollywood. Movie 43 is not for the easily-offended and contains jaw-dropping, sometimes shockingly disturbing, but always entertaining intertwined storylines you’ll have to see to believe.”

In alphabetical order, the cast is headed up by Elizabeth Banks, Kristen Bell, Halle Berry, Leslie Bibb, Kate Bosworth, Gerard Butler, Kieran Culkin, Josh Duhamel, Anna Faris, Richard Gere, Terrence Howard, Hugh Jackman, Johnny Knoxville, Justin Long, Christopher Mintz-Plasse, Chloë Grace Moretz, Liev Schreiber, Seann William Scott, Emma Stone, Jason Sudeikis, Uma Thurman, Naomi Watts, and Kate Winslet.

Behind the camera are Steven Brill, Peter Farrelly, Will Graham, Steve Carr, Griffin Dunne, James Duffy, Jonathan Van Tulleken, Elizabeth Banks, Patrik Forsberg, Brett Ratner, Rusty Cundieff, and James Gunn.

And penning the script, we have Will Carlough, Tobias Carlson, Jacob Fleisher, Patrik Forsberg, Will Graham, James Gunn, Claes Kjellstrom, Jack Kukoda, Bill O’Malley, Matthew Portenoy, Greg Pritikin, Rocky Russo, Olle Sarri, Elizabeth Shapiro, Jeremy Sosenko, Jonathan Van Tulleken, and Jonas Wittenmark.

Movie 43 will be released in the US on 25th January, 2013, followed by a 1st February release here in the UK. I can’t wait. This looks pretty brilliant. For now, here’s the great new red-band preview – one final reminder, this isn’t work-appropriate viewing, so be sure to come back to watch this later if you’re reading this at your desk. Enjoy.