Winstead will star opposite Benjamin Walker (Kinsey), Anthony Mackie (The Hurt Locker) and Dominic Cooper (Tamara Drewe) in the adaptation of Seth Grahame-Smith’s mash-up novel.
President Lincoln’s mother is killed by a supernatural creature, which fuels his passion to crush vampires and their slave-owning helpers.
Timur Bekmambetov (Wanted) is attached to direct, with production expected to start soon.
Abraham Lincoln: Vampire Hunter will be released on August 22, 2012.
Winstead will next be seen in The Thing.