Robert De Niro, Rose Byrne and Bobby Cannavale have been set to star in the upcoming road-trip comedy ‘Inappropriate Behavior.’

De Niro, Byrne and Cannavale join Vera Farmiga, Rainn Wilson, Whoopi Goldberg and newcomer William Fitzgerald on the cast.

The movie follows Max Bernal (Cannavale), a once-successful late-night comedy writer turned not-so-successful stand-up comic, who moves in with his father (De Niro), having recently blown up his career and marriage. When he and his ex-wife Jenna (Byrne) find themselves at odds with how to address the needs of their 11-year-old autistic son Ezra (Fitzgerald), Max decides to kidnap his child and take him on a cross-country odyssey … with comically disastrous results.

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Tony Goldwyn is directing the film from an original script written by Tony Spiridakis. Goldwyn and Spiridakis will also serve as producers on the film, along with Jon Kilik. Additional producers include William Horberg and Zhang Xin on behalf of Closer Media; and Steve Sarowitz, Justin Baldoni, Manu Gargi and Andrew Calof for Wayfarer Studios. Jason Pinardo, Cannavale and Lois Robbins will executive produce.

Production is due to commence on the project towards the end of September.