Betty Thomas (Alvin and the Chipmunks: The Squeakquel) is in talks to direct Universal Pictures’ new comedy film Desperados.

Wayne McClammy was originally attached to direct, but left citing creative differences.

Desperados, a starring vehicle for Isla Fisher (Rango), is written by Ellen Rapoport and described as a female-oriented version of The Hangover, much like the Judd Apatow-produced Bridesmaids.

A woman (Fisher) sends an indignant email to her new beau, who has gone silent after they have sex, only to discover he’s comatose in a Mexican hospital. Panicking, she races south of the border with her friends in tow to intercept the email before he recovers.

Source: THR