Angelina Jolie is set to headline ‘The Initiative,’ a high-octane spy thriller that will reunite her with ‘Mr. and Mrs. Smith’ director Doug Liman.

The project, currently generating significant buzz in Hollywood, is written by F. Scott Frazier (Collide, xXx: The Return of Xander Cage), with Jeff Kirschenbaum producing under the Roth/Kirschenbaum Films banner. While plot details are being kept tightly under wraps, the combination of Jolie’s commanding screen presence and Liman’s trademark kinetic action style promises an explosive return to the espionage genre.

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Universal Pictures is reportedly in talks to secure the project, which is already shaping up to be a sought-after package on the market.

Jolie, an Oscar winner and global box-office draw, last ventured into spy territory with 2010’s ‘Salt.’ Her reunion with Liman marks the first time the pair have worked together since the 2005 action-romance ‘Mr. and Mrs. Smith,’ which became a cultural touchstone and a $487 million worldwide hit.

With its powerhouse creative team and a star known for redefining action-hero roles, ‘The Initiative’ is poised to be one of the most anticipated thrillers in development.