9. Weapon X
In the comic books, Deadpool received his abilities from Weapon X, the same clandestine government operation responsible for coating Wolverine’s skeleton in Adamantium. However, with Mystique taking William Stryker’s place at the end of X-Men: Day of Future Past, does Weapon X no longer exist? Well, while Wade Wilson is taken to some sort of mysterious facility in the trailer, director Tim Miller seemingly confirmed in a recent chat with Empire that those in charge aren’t the same men behind Weapon X. Why this change has been made is hard to say, though with the events of X-Men Origins: Wolverine no longer canon, it could be that the filmmakers want to differentiate that version of Deadpool from this updated one!